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1.
China Journal of Chinese Materia Medica ; (24): 5137-5143, 2021.
Article in Chinese | WPRIM | ID: wpr-921655

ABSTRACT

Mongolians have a long history of using prescriptions, which can be classified into four stages as follows: the germination and experience accumulation stage before the 13 th century, the theoretical formation stage from the 13 th to 16 th century, the rapid development stage from the 17 th to 20 th century, and the leaping development stage from the mid-20 th century to the present. The prescriptions from the ancient classical or representative medical books have always been used by Mongolian physicians for generations, and they are still in use due to the definite curative effects. In 2008, the Notice on Issuing the Supplementary Provisions to the Registration and Management of Traditional Chinese Medicine(TCM) described that China has attached more importance to the excavation and development of classical prescriptions. As stipulated in the Law of the People's Republic of China on Traditional Chinese Medicine, the classical prescriptions should be those available in ancient TCM classics and still in wide use, with exact curative effects, distinct features, and obvious advantages. This paper expounded the historical formation and development of classical prescriptions in Mongo-lian medicine, introduced the five most influential ancient medical books revealing the formation and development of these classic prescriptions, and traced the origin of such classical prescriptions as Wenguanmu Siwei Decoction, Shouzhangshen Bawei Decoction, Jianghuang Siwei Decoction and summarized the origin, development history and characteristics of classical prescriptions in Mongolian medicine, aiming to provide a reference for their further research and development.


Subject(s)
Humans , Books , China , Drugs, Chinese Herbal , Medicine, Chinese Traditional , Medicine, Mongolian Traditional , Prescriptions
2.
China Journal of Chinese Materia Medica ; (24): 1258-1262, 2013.
Article in Chinese | WPRIM | ID: wpr-350622

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects and immunoregulation mechanism of the traditional Mongolian medicine Wuweifengshi capsule on adjuvant arthritis (AA).</p><p><b>METHOD</b>Wister rats were divided into several groups: normal group, AA model group, Wuweifengshi capsule groups (with low, moderate, high dose of 0.2, 0.4, 0.8 g x kg(-1) x d(-1) respectively), and Zhonglun-5 group (original dose of 1.68 g x kg(-1) x d(-1)). The edema degree, the level of IL-1beta, TNF-alpha, PGE2, NO and MDA and the activity of SOD in serum were detected. Through cell culture, the effects of the medicine on AA rat's splenic cell's multiplication capacity were studied. The influence of celiac macrophage cell culture fluid of AA rats' on C57BL/6J mice thymic cell multiplication capacity under the medicine was evaluated.</p><p><b>RESULT</b>Wuweifengshi capsule showed an inhibiting function on the level of IL-1beta, TNF-alpha, PGE2, NO and increased the activity of SOD in serum, but showed no significant influence on MDA. It also inhibited the AA rat's splenic cell's multiplication capacity and the influence of celiac macrophage cell culture fluid of AA rat's on C57BL/6J mice thymic cell multiplication capacity.</p><p><b>CONCLUSION</b>The anti-AA effect of Wuweifengshi capsule is possibly due to its inhibition of relevant cytokines and its adjustment of corresponding enzyme's activity and immunization organ's cell multiplication capacity.</p>


Subject(s)
Animals , Female , Male , Mice , Rats , Arthritis, Experimental , Drug Therapy , Allergy and Immunology , Metabolism , Pathology , Capsules , Dehydroascorbic Acid , Blood , Dinoprostone , Metabolism , Disease Models, Animal , Edema , Drug Therapy , Interleukin-1beta , Metabolism , Lymphocytes , Allergy and Immunology , Metabolism , Macrophages, Peritoneal , Metabolism , Medicine, Mongolian Traditional , Nitric Oxide , Metabolism , Spleen , Cell Biology , Metabolism , Superoxide Dismutase , Blood , Tumor Necrosis Factor-alpha , Metabolism
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